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94. Frage
Which of the following is the BEST strategy for reducing bloodstream infections associated with central venous catheters?
Antwort: D
Begründung:
* Chlorhexidine-impregnated dressings reduce central line-associated bloodstream infections (CLABSI) by preventing bacterial colonization.
* Routine catheter replacement (A) increases insertion risks without reducing infections.
* Daily blood cultures (C) are unnecessary and lead to false positives.
* Povidone-iodine (D) is less effective than chlorhexidine for skin antisepsis.
CBIC Infection Control References:
* APIC Text, "CLABSI Prevention Measures," Chapter 10.
95. Frage
The Infection Prevention and Control Committee is concerned about an outbreak of Serratia marcescens in the intensive care unit. If an environmental source is suspected, the BEST method to validate this suspicion is to
Antwort: C
Begründung:
The correct answer is C, "obtain surface cultures," as this is the best method to validate the suspicion of an environmental source for an outbreak of Serratia marcescens in the intensive care unit (ICU). According to the Certification Board of Infection Control and Epidemiology (CBIC) guidelines, Serratia marcescens is an opportunistic gram-negative bacterium commonly associated with healthcare-associated infections (HAIs), often linked to contaminated water, medical equipment, or environmental surfaces in ICUs. Obtaining surface cultures allows the infection preventionist (IP) to directly test environmental samples (e.g., from sinks, ventilators, or countertops) for the presence of Serratia marcescens, providing microbiological evidence to confirm or rule out an environmental source (CBIC Practice Analysis, 2022, Domain II: Surveillance and Epidemiologic Investigation, Competency 2.2 - Analyze surveillance data). This method is considered the gold standard for outbreak investigations when an environmental reservoir is suspected, as it offers specific pathogen identification and supports targeted interventions.
Option A (apply fluorescent gel) is a technique used to assess cleaning efficacy by highlighting areas missed during disinfection, but it does not directly identify the presence of Serratia marcescens or confirm an environmental source. Option B (use ATP system) measures adenosine triphosphate (ATP) to evaluate surface cleanliness and organic residue, which can indicate poor cleaning practices, but it is not specific to detecting Serratia marcescens and lacks the diagnostic precision of cultures. Option D (perform direct practice observation) is valuable for assessing staff adherence to infection control protocols, but it addresses human factors rather than directly validating an environmental source, making it less relevant as the initial step in this context.
The focus on obtaining surface cultures aligns with CBIC's emphasis on using evidence-based methods to investigate and control HAIs, enabling the IP to collaborate with the committee to pinpoint the source and implement corrective measures (CBIC Practice Analysis, 2022, Domain II: Surveillance and Epidemiologic Investigation, Competency 2.3 - Identify risk factors for healthcare-associated infections). This approach is supported by CDC guidelines for outbreak investigations, which prioritize microbiological sampling to guide environmental control strategies (CDC Guidelines for Environmental Infection Control in Healthcare Facilities, 2019).
References: CBIC Practice Analysis, 2022, Domain II: Surveillance and Epidemiologic Investigation, Competencies 2.2 - Analyze surveillance data, 2.3 - Identify risk factors for healthcare-associated infections.
CDC Guidelines for Environmental Infection Control in Healthcare Facilities, 2019.
96. Frage
A hospital is experiencing an increase in vancomycin-resistant Enterococcus (VRE) infections in the hematology-oncology unit. Which of the following interventions is MOST effective in halting the spread of VRE in this high-risk setting?
Antwort: C
Begründung:
Comprehensive and Detailed In-Depth Explanation:
Hand hygiene remains the single most effective intervention to prevent the spread of vancomycin-resistant Enterococcus (VRE) in healthcare settings. Implementing an audit and feedback system significantly improves compliance and reduces VRE transmission.
Step-by-Step Justification:
* Hand Hygiene Compliance Audit and Feedback (Best Strategy)
* Studies show that poor hand hygiene is the primary mode of VRE transmission in hospitals.
* Implementing real-time auditing with feedback ensures sustained compliance and helps identify weak areas.
* Why Other Options Are Incorrect:
* A. Screening all patients and isolating VRE-positive patients:
* While screening helps identify carriers, contact precautions alone are not sufficient without strong hand hygiene enforcement.
* B. Restricting vancomycin use:
* While antimicrobial stewardship is crucial, vancomycin use alone does not drive VRE outbreaks-poor infection control practices do.
* D. Conducting environmental sampling weekly:
* Routine sampling is not necessary; immediate terminal disinfection and improved hand hygiene are more effective.
CBIC Infection Control References:
* APIC Text, "VRE Prevention and Hand Hygiene," Chapter 11.
* APIC-JCR Workbook, "Antimicrobial Resistance and Infection Control Measures," Chapter 7.
97. Frage
The infection preventionist (IP) is assisting pharmacists in investigating medication contamination at the hospital's compounding pharmacy. As part of the medication recall process, the IP should:
Antwort: A
Begründung:
The scenario involves an infection preventionist (IP) assisting pharmacists in addressing medication contamination at the hospital's compounding pharmacy, with a focus on the medication recall process. The IP' s role is to apply infection control expertise to mitigate risks, guided by the Certification Board of Infection Control and Epidemiology (CBIC) principles and best practices. The recall process requires a systematic approach to identify, contain, and resolve the issue, and the "first" or most critical step must be determined.
Let's evaluate each option:
* A. Have laboratory culture all medication: Culturing all medication to confirm contamination is a valuable step to identify affected batches and guide the recall. However, this is a resource-intensive process that depends on first understanding the scope and source of the problem. Without identifying the potential source of contamination, culturing all medication could be inefficient and delay the recall.
This step is important but secondary to initial investigation.
* B. Inspect for safe injection practices: Inspecting for safe injection practices (e.g., single-use vials, proper hand hygiene, sterile technique) is a critical infection control measure, especially in compounding pharmacies where contamination often arises from procedural errors (e.g., reuse of syringes, improper cleaning). While this is a proactive step to prevent future contamination, it addresses ongoing practices rather than the immediate recall process for the current contamination event. It is a complementary action but not the first priority.
* C. Identify the potential source of contamination: Identifying the potential source of contamination is the foundational step in the recall process. This involves investigating the compounding environment (e.
g., water quality, equipment, personnel practices), raw materials, and production processes to pinpoint where the contamination occurred (e.g., bacterial ingress, cross-contamination). The CBIC emphasizes root cause analysis as a key infection prevention strategy, enabling targeted recalls, corrective actions, and prevention of recurrence. This step is essential before culturing, inspecting, or notifying patients, making it the IP's primary responsibility in this context.
* D. Inform all discharged patients of potential medication contamination: Notifying patients is a critical step to ensure public safety and allow for medical follow-up if they received contaminated medication.
However, this action requires prior identification of the contaminated batches and their distribution, which depends on determining the source and confirming the extent of the issue. Premature notification without evidence could cause unnecessary alarm and is not the first step in the recall process.
The best answer is C, as identifying the potential source of contamination is the initial and most critical step in the medication recall process. This allows the IP to collaborate with pharmacists to trace the contamination, define the affected products, and guide subsequent actions (e.g., culturing, inspections, notifications). This aligns with CBIC's focus on systematic investigation and risk mitigation in healthcare-associated infection events.
References:
* CBIC Infection Prevention and Control (IPC) Core Competency Model (updated 2023), Domain III:
Prevention and Control of Infectious Diseases, which includes identifying sources of contamination in healthcare settings.
* CBIC Examination Content Outline, Domain V: Management and Communication, which emphasizes root cause analysis during outbreak investigations.
* CDC Guidelines for Safe Medication Compounding (2022), which recommend identifying contamination sources as the first step in a recall process.
98. Frage
What is a characteristic of immediate-use steam sterilization?
Antwort: B
Begründung:
The correct answer is C, "Substitute for maintaining sufficient amounts of sterile instruments," as this is a characteristic of immediate-use steam sterilization (IUSS). According to the Certification Board of Infection Control and Epidemiology (CBIC) guidelines, IUSS, formerly known as flash sterilization, is a process designed to rapidly sterilize items that are needed urgently when pre-sterilized inventory is unavailable or insufficient. It serves as a temporary solution to address gaps in sterile instrument availability, such as during unexpected surges in surgical demand or equipment shortages, provided strict protocols are followed (CBIC Practice Analysis, 2022, Domain III: Infection Prevention and Control, Competency 3.3 - Ensure safe reprocessing of medical equipment). However, IUSS is not a routine practice and should be minimized due to its limitations, including the lack of immediate biologic indicator results.
Option A (alternative to purchasing expensive instrument sets) is incorrect because IUSS is not intended as a cost-saving measure or a replacement for acquiring necessary equipment; it is a contingency process. Option B (can be used for the following surgery if properly stored) is misleading, as IUSS items are intended for immediate use and not for storage or use in subsequent procedures, which requires standard sterilization cycles with proper packaging and validation. Option D (performed in emergencies where cleaning is the most critical step) overemphasizes cleaning and mischaracterizes IUSS; while cleaning is a critical initial step, the process is defined by its rapid sterilization for emergency use, not solely by cleaning priority.
The characteristic of substituting for insufficient sterile instruments aligns with CBIC's focus on ensuring safe reprocessing practices while acknowledging the practical challenges in healthcare settings (CBIC Practice Analysis, 2022, Domain III: Infection Prevention and Control, Competency 3.5 - Evaluate the environment for infection risks). This is supported by AAMI ST79, which outlines IUSS as a last-resort measure to maintain surgical readiness (AAMI ST79:2017).
References: CBIC Practice Analysis, 2022, Domain III: Infection Prevention and Control, Competencies 3.3 - Ensure safe reprocessing of medical equipment, 3.5 - Evaluate the environment for infection risks. AAMI ST79:2017, Comprehensive guide to steam sterilization and sterility assurance in health care facilities.
99. Frage
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